Corrigendum to “Oxidative Stress-Related Parthanatos of Circulating Mononuclear Leukocytes in Heart Failure”
نویسندگان
چکیده
منابع مشابه
Oxidative Stress-Related Parthanatos of Circulating Mononuclear Leukocytes in Heart Failure
Background The present study aims to examine the oxidative stress-related activation of poly(ADP-ribose) polymerase (PARP), a cause of parthanatos in circulating mononuclear leukocytes of patients with chronic heart failure (CHF), that was rarely investigated in the human setting yet. Methods Patients with CHF (n = 20) and age- and body mass index-matched volunteers (n = 15) with a normal hea...
متن کاملOxidative stress and heart failure.
Oxidative stress, defined as an excess production of reactive oxygen species (ROS) relative to antioxidant defense, has been shown to play an important role in the pathophysiology of cardiac remodeling and heart failure (HF). It induces subtle changes in intracellular pathways, redox signaling, at lower levels, but causes cellular dysfunction and damage at higher levels. ROS are derived from se...
متن کاملTargeting Mitochondrial Oxidative Stress in Heart Failure
Oxidative stress contributes to various cardiovascular diseases and aging and was causally linked to the progression of heart failure (1,2). Among the most relevant sources for reactive oxygen species (ROS) are nicotinamide adenine dinucleotide phosphate (NADPH) oxidases and mitochondria (1,3–7). The ROS impair excitation-contraction coupling, cause arrhythmias, and contribute to cardiac remode...
متن کاملTargeting oxidative stress in heart failure
Increased oxidative stress is recognized to be important in the pathogenesis of cardiovascular disease, including heart failure. Reactive oxygen species (ROS) can be derived from diverse sources, including mitochondria, NADPH oxidase, and xanthine oxidase. Many agents established in the treatment of heart failure (including angiotensin-converting enzyme inhibitors, statins, b-blockers, hydralaz...
متن کاملDiagnostic, Prognostic, and Therapeutic Value of Circulating miRNAs in Heart Failure Patients Associated with Oxidative Stress
Heart failure is a major public health problem especially in the aging population (≥65 years old), affecting nearly 5 million Americans and 15 million European people. Effective management of heart failure (HF) depends on a correct and rapid diagnosis. Presently, BNP (brain natriuretic peptide) or N-terminal pro-brain natriuretic peptide (NT-proBNP) assay is generally accepted by the internatio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2019
ISSN: 1942-0900,1942-0994
DOI: 10.1155/2019/8747486